Naratriptan hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

那拉曲坦盐酸盐是那拉曲坦的盐酸盐形式，那拉曲坦是一种磺酰胺，具有选择性血清素 (5-HT) 1 受体激动活性和抗偏头痛特性。

Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.

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Naratriptan HCl | Amerge | Naramig | GR-85548A

Others

Other Targets

5-HT1

Neurological Disease

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143388-64-1

371.93

C17H25N3O2S·HCl

>98% (HPLC)

DMSO : ≥ 35 mg/mL; 94.10 mM

CNS(=O)(=O)CCc1cc2c(cc1)[nH]cc2C1CCN(CC1)C.Cl

N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide hydrochloride

(-20℃)

With Ice Pack

≥ 2 years